The U.S. and Israel launched strikes against Iran in an attack early Saturday morning on the country’s capital on, according to the Associated Press, as talks over Iran’s nuclear program failed to produce the result President Donald Trump desired. 

Targets of the strikes were not immediately clear.

Israel launched a “preemptive” strike against Iran early Saturday, Israeli Defense Minister Israel Katz announced.

He described the attack as being done “to remove threats,” according to a statement.

The Israeli government declared a state of alert across the country because of the expectation of Iranian retaliation. “This is a proactive alert to prepare the public for the possibility of missiles being launched toward the State of Israel,” the Israel Defense Forces said in a post on X.

The Associated Press reported that a cloud of smoke was rising from Tehran’s downtown area. The apparent strike happened near the offices of Supreme Leader Ayatollah Ali Khamenei, according to the AP report.